Polyomavirus middle T protein encoded by a retrovirus transforms nonestablished chicken embryo cells

  • Kaplan P
  • Simon S
  • Eckhart W
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Abstract

A murine retrovirus encoding the middle T protein of polyomavirus infected and transformed nonestablished chicken embryo cells. The infected cultures formed colonies in soft agar-containing medium and released infectious transforming virus. Middle T protein expressed in the transformed chicken cells associated with p60c-src and, in immunoprecipitates, enhanced the tyrosine protein kinase activity of p60c-src.

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Kaplan, P. L., Simon, S., & Eckhart, W. (1985). Polyomavirus middle T protein encoded by a retrovirus transforms nonestablished chicken embryo cells. Journal of Virology, 56(3), 1023–1026. https://doi.org/10.1128/jvi.56.3.1023-1026.1985

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