Abstract
An elastic model for the supercoiling of duplex DNA is developed. The simplest assumptions regarding the elastic properties of double-helical DNA (homogeneous, isotropic, of circular cross section, and remaining straight when unstressed) will generate two orders of superhelicity when stressed. Recent experimental results [Brady, G.W., Fein, D.B. & Brumberger, H. (1976) Nature 264, 231-234] suggest that in supercoiled DNA molecules there are regions where two distinct orders of supercoiling arise, as predicted by this model.
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CITATION STYLE
Benham, C. J. (1977). Elastic model of supercoiling. Proceedings of the National Academy of Sciences of the United States of America, 74(6), 2397–2401. https://doi.org/10.1073/pnas.74.6.2397
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