Preliminary result on finding treatments for patients with comorbidity

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Abstract

According to some research, comorbidity is reported in 35 to 80% of all ill people [1]. Multiple guidelines are needed for patients with comorbid diseases. However, it is still a challenging problem to automate the application of multiple guidelines to patients because of redundancy, contraindicated, potentially discordant recommendations. In this paper, we propose a mathematical model for the problem. It formalizes and generalizes a recent approach proposed by Wilk and colleagues. We also demonstrate that our model can be encoded, in a straightforward and simple manner, in Answer Set Programming (ASP)-a class of Knowledge Representation languages. Our preliminary experiment also shows our ASP based implementation is efficient enough to process the examples used in the literature.

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Zhang, Y., & Zhang, Z. (2014). Preliminary result on finding treatments for patients with comorbidity. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 8903, pp. 14–28). Springer Verlag. https://doi.org/10.1007/978-3-319-13281-5_2

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