Outcome of Vaginal Progesterone as a Tocolytic Agent: Randomized Clinical Trial

  • Saleh Gargari S
  • Habibolahi M
  • Zonobi Z
  • et al.
N/ACitations
Citations of this article
19Readers
Mendeley users who have this article in their library.

Abstract

Vaginal progesterone has a potential beneficial effect in postponing of preterm labor by suppression of prostaglandins cascades. Although different studies evaluated the use of progesterone for preterm birth, the exact effect of which on prolongation of pregnancy remains unclear. Seventy two women who underwent preterm labor were managed by magnesium sulfate. Then they were randomly assigned to continue pregnancy either by applying vaginal progesterone (400 mg) until delivery or without using any drug. Gestational age mean at the time of delivery and postponing delivery mean time were significantly higher in progesterone group. Comparison of neonatal outcomes between two groups of patients showed meaningful benefits of progesterone in increasing of neonatal weight, reduction of low birth weight babies, and lowing neonate admitted in NICU.

Cite

CITATION STYLE

APA

Saleh Gargari, S., Habibolahi, M., Zonobi, Z., Khani, Z., Sarfjoo, F. S., Kazemi Robati, A., … Karimi, Z. (2012). Outcome of Vaginal Progesterone as a Tocolytic Agent: Randomized Clinical Trial. ISRN Obstetrics and Gynecology, 2012, 1–5. https://doi.org/10.5402/2012/607906

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free