Modeling the current modulation of bundled DNA structures in nanopores

4Citations
Citations of this article
6Readers
Mendeley users who have this article in their library.
Get full text

Abstract

We investigate the salt-dependent current modulation of bundled DNA nanostructures in a nanopore. To this end, we developed four simulation models for a 2 × 2 origami structure with increasing level of detail ranging from the mean-field level to an all-atom representation of the DNA structure. We observe a consistent pore conductivity as a function of salt concentration for all four models. However, a comparison of our data to recent experimental investigations on similar systems displays significant deviations. We discuss possible reasons for the discrepancies and propose extensions to our models for future investigations.

Cite

CITATION STYLE

APA

Szuttor, K., Weik, F., Grad, J. N., & Holm, C. (2021). Modeling the current modulation of bundled DNA structures in nanopores. Journal of Chemical Physics, 154(5). https://doi.org/10.1063/5.0038530

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free