Tumours and cancers in Graeco-Roman times

Abstract

In Graeco-Roman times all tumours (Greek: onkoi, abnormal swellings) were considered to be of inflammatory origin, the results of unfavourable humoural fluxes, and caused by an extravascular outpouring of fluid into tissue spaces. The neoplastic nature of tumours is a more recent concept, barely two centuries old. In Hippocratic literature tumours were mainly classified as karkinômata, phumata, and oidêmata. Phumata included a large variety of tumours, inflammatory and neoplastic in origin, and mostly beningn (in modern terms), while oidêmata were soft, painless tumours and even included generalises oedema (dropsy). Although all categories possibly included occasional cancers, the vast majority of what appears to have been malignant tumours were called karkinoi karkinômata (Latin: cancrum/carcinoma). There was, however, no recognition of benign and malignant, primary and secondary tumours, in the modern sense.