The immunosuppressive action of regulatory T (Treg) cells is one mechanism attributed to the limited success of cancer immunotherapies with checkpoint blockers. Two recent studies report distinct transcriptional profiles of tumor-infiltrating Tregcells and expression of specific molecules, suggesting novel strategies to overcome resistance to cancer immunotherapy.
CITATION STYLE
Finotello, F., & Trajanoski, Z. (2017, January 27). New strategies for cancer immunotherapy: Targeting regulatory T cells. Genome Medicine. BioMed Central Ltd. https://doi.org/10.1186/s13073-017-0402-8
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