How should a nonfunctioning pituitary macroadenoma be monitored after debulking surgery?

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Abstract

Transsphenoidal surgery is the treatment of choice for nonfunctioning pituitary macroadenomas but is seldom curative. Tumour progression rates are high in patients with postoperative remnants. Therefore, long-term monitoring is necessary to detect tumour growth, which may be asymptomatic or manifest with visual field defects and/or pituitary dysfunction. In view of the generally slow-growing nature of these tumours, yearly magnetic resonance imaging, neuro-ophalmologic and pituitary function evaluation are appropriate during the first 3-5 years after surgery. If there is no evidence for tumour progression during this period, testing intervals may be extended thereafter. © 2009 Blackwell Publishing Ltd.

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Greenman, Y., & Stern, N. (2009). How should a nonfunctioning pituitary macroadenoma be monitored after debulking surgery? Clinical Endocrinology, 70(6), 829–832. https://doi.org/10.1111/j.1365-2265.2009.03542.x

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