Automated identification and analysis of visual micro-experiments on cellular microarray

Abstract

This paper is an overview of the computer-based tools I designed at Institut Pasteur Korea in order to analyse a large quantity of microscopy cell based experiments. This development consisted in designing algorithms and software for automatically localize, identify and analyze cells on spots of cellular microarray at high resolution. We believe the applications of this work are numerous from genome wide loss of function screens to drug target deconvolution assays and diagnostic. © 2012 Springer Berlin Heidelberg.