Regioselective Introduction of a Methoxy Group at the Benzylic Position of Isochromane Derivatives by Cerium(IV) Oxidation in Methanol

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Abstract

The oxidation of methoxy-isochromans and -isochromanones with ceric ammonium nitrate in methanol introduced a new methoxy group regioselectively at a benzylic position Dara to the methoxy function on the aromatic nucleus. © 1989, The Pharmaceutical Society of Japan. All rights reserved.

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Tsuda, Y., Isobe, K., Takeda, N., & Mohri, K. (1989). Regioselective Introduction of a Methoxy Group at the Benzylic Position of Isochromane Derivatives by Cerium(IV) Oxidation in Methanol. Chemical and Pharmaceutical Bulletin, 37(12), 3390–3392. https://doi.org/10.1248/cpb.37.3390

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