Vladinol f, neolignan compound from the stem bark of dryobalanops oblongifolia (Dipterocarpaceae) and antiplasmodial activity

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Abstract

Drybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis of UV-Vis, NMR, and MS spectra and a comparison with the reference. In vitro test of this compound against Plasmodium falciparum 3D7 showed that IC50 value was 3.51 μg/mL.

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Indriani, Aminah, N. S., Puspaningsih, N. N. T., Hasna, I. H., Takaya, Y., & Satrimafitrah, P. (2021). Vladinol f, neolignan compound from the stem bark of dryobalanops oblongifolia (Dipterocarpaceae) and antiplasmodial activity. Rasayan Journal of Chemistry, 14(1), 161–165. https://doi.org/10.31788/RJC.2021.1416017

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