Ex vivo expansion of cord blood

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Abstract

Umbilical cord blood (CB) provides an alternate source for patients undergoing high-dose chemotherapy for treatment of cancer or genetic diseases. In particular, CB has become a standard therapeutic option for selected patients with hematologic malignancies. Several studies have reported on the use of CB for transplantation in adult patients; however, the low cell doses have limited the use of CB in this setting due to subsequent delays in engraftment. Ex vivo expansion is an approach that is being explored as a means to provide larger cell numbers from CB products. © Springer-Verlag London Limited 2009.

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McNiece, I. K., & Shpall, E. J. (2009). Ex vivo expansion of cord blood. In Frontiers of Cord Blood Science (pp. 91–96). Springer London. https://doi.org/10.1007/978-1-84800-167-1_4

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