Introduction to microfluidics

Abstract

Microfluidics-the manipulation and analysis of minute volumes of fluid-has emerged as a powerful technology with many established and relevant applications within the biological sciences. Over three decades of research has yielded a wealth of techniques for improving biological assays through both the miniaturization of existing methods, as well as the development of novel analytical approaches. In this introductory chapter we provide an overview of microfluidic technology, beginning with a historical look at the field's origins. We also present brief synopses of the fundamental physical phenomena driving microfluidics, the techniques employed in device fabrication, and biological applications that have benefited from microfluidic implementation. Finally we conclude with an outlook to the future of the field as microfluidic technology shifts from research laboratories into commercial ventures. This chapter is meant to familiarize readers who may be new to the field of microfluidics, while highlighting areas that will be explored in more detail throughout the text. © 2008 Springer Science+Business Media, LLC.