Effect of an improved local ingredient-based complementary food fortified or not with iron and selected multiple micronutrients on Hb concentration

Abstract

Objective To assess the effect of an improved local ingredient-based gruel fortified or not with selected multiple micronutrients (MM) on Hb concentration of young children.Design In a nutrition centre that we opened in their villages, children received either MM supplement (containing iron, zinc, vitamin A, vitamin C and iodine) with the improved gruel (MMGG) or the improved gruel only (GG), twice daily, 6 d/week, for 6 months. We assessed baseline and endpoint Hb concentration and anthropometric indices.Setting Kongoussi, a rural and poor district of Burkina Faso.Subjects In a community-based trial, we randomly assigned 131 children aged 6-23 months with Hb concentrations in the range of 80-109 g/l into two groups.Results The groups did not differ significantly at baseline. Mean baseline Hb concentration was 892 (sd 65) g/l and 903 (sd 84) g/l in the GG and the MMGG, respectively (P = 042). It increased to 1041 (sd 114) g/l in the GG (P < 0001) and 1076 (sd 147) g/l in the MMGG (P < 0001). The between-group difference of 35 (95 % CI 10, 81) g/l in mean (sd) endpoint Hb concentration was not significant (P = 013). The endpoint anthropometric indices were not different between the groups.Conclusions This MM supplement had no additional effect on Hb concentration. Thorough studies are needed to evaluate the actual efficacy of the gruel before its introduction into household routine. Copyright © 2010 The Authors.