Anticancer and nutraceutical potentialities of phytase/phytate

Abstract

In the past few years, both phytase and phytate have gained a special place in the biotechnological sector at large and biomedical sector in particular. Phytase belongs to a group of novel organic phosphorus-containing compounds which are widely distributed in nature. The scientific literature is witnessed of a significant landmark in phytase research with the discovery that not all phytases share identical catalytic mechanisms. In this context, many research scientists or research based organizations, around the globe, have already been or being directed or redirecting their research interests on designing and engineering ideal phytase-based bio-products for targeted applications in various sectors of the modern world. Many efforts have been made on the biotechnological valorization of this potent enzyme. However, the current literature still lacks with its biomedical valorization. Though, the information on medical perspectives of phytase and phytate is very scarce and scattered. Therefore, herein an effort has been made to discuss the anticancer and nutraceutical potentialities of phytase or phytate at one place. Besides from the anticancer potential, phytase/phytate also have numerous health benefits e.g. the physiological presence of phytate in our body, close association of phytate-rich diet with low incidence of numerous diseases and vice versa.