Abstract
A functional genomic approach, based on systematic data gathering, was used to characterize a family of proteins containing a triparite motif (TRIM). A total of 37 TRIM genes/proteins were studied, 21 of which were novel. The results demonstrate that TRIM proteins share a common function: by means of homo-multimerization they identify specific cell compartments.
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Reymond, A., Meroni, G., Fantozzi, A., Merla, G., Cairo, S., Luzi, L., … Ballabio, A. (2001). The tripartite motif family identifies cell compartments. EMBO Journal, 20(9), 2140–2151. https://doi.org/10.1093/emboj/20.9.2140
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