Common data model and database system development for the Korea biobank network

Abstract

The importance of clinical information related to specimens is increasing due to the research on human biological specifications being conducted worldwide. In order to utilize data, it is necessary to define the range of data and develop a standardized system for collected resources. The purpose of this study is to establish clinical information standardization and to allow clinical information management systems to improve the utilization of biological specifications. The KBN CDM, consisting of 18 tables and 177 variables, was developed. The clinical information codes were mapped in standard terms. The 27 diseases in the group were collected from 17 biobanks, and all disorders not belonging to the group were standardized and loaded. We also developed a system that provides statistical visualization screens and data retrieval tools for data collection. This study developed a unified management system to model KBN CDM that collects standardized data, manages clinical information, and shares the information systematically. Through this system, all participating biobanks can be integrated into one system for integrated management and research.