Nonlinear systems biology and design surface design

Abstract

The intentof this paper is to jointly investigate fundamental processes inliving systems, their potential applicationinthe novel designof responsive surfaces and spatial structures,and their applicability inbiomedicine. Through the investigation of organotypic biological models designed to recapitulate breast tissue homeostasis and cancer,parallel models work to unfold the parametric logic of these biological and responsive membrane and scaffold structures,thereby revealing their deep interior logics. The result is an abstract surface architecture capable of responding dynamically to both environment (context) and to deeper interior programmed systems.