Nanoparticles for dentin tissue stabilization

Abstract

Nanotechnology has been applied to manage previously infected dentin. These treatment procedures are aimed for non- invasive elimination of residual bacterial biofilms, improve the resistance of dentin to enzymatic (host/bacterial-mediated) degradation and improve the mechanical integrity of dentin matrix. This chapter discusses the issues associated with previously infected dentin, strategies used to strengthen dentin tissue matrix and current progress/potential applications of various functional nanoparticles for the physical, chemical and mechanical stabilization of dentin. Nanoparticles of various materials (polymers, metals), size and shape as well as modifications are available depending on the requirement. Nanoparticles could be tailored to perform specific or multiple functions based on the tissue-specific requirements. Carefully tailored nanoparticles with sound scientific basis on the mechanism of action, safety and dose will find potential advantage in minimally invasive/non-invasive dentin tissue stabilization.