Capsaicin on the viability of random-pattern skin flaps in rats

10Citations
Citations of this article
7Readers
Mendeley users who have this article in their library.

Abstract

Purpose: To evaluate the effects of capsaicin on the viability of ischemic random-pattern skin flaps in rats. Methods: Forty EPM1-Wistar rats were randomized into two groups of 20 animals each, the capsaicin group and the control group. A random-pattern skin flap measuring 10 x 4cm was raised and a plastic barrier was placed between the flap and the donor site. After the surgical procedure, the control group was treated with an inert vehicle in the form of a cream applied uniformly to a rayon bandage which, in turn, was applied to the surface of the skin flap. The capsaicin group was treated in the same way, but in this case capsaicin was added to the cream. This procedure was repeated for two consecutive days. Results: There was a significantly smaller amount of flap necrosis in the capsaicin group (35.07%) than in the control group (44.75%) (p=0.035). Conclusion: Topical administration of capsaicin improved the viability of ischemic random-pattern skin flaps in rats.

References Powered by Scopus

The design of a pedicle flap in the rat to study necrosis and its prevention

380Citations
N/AReaders
Get full text

Skin flap failure: Pathophysiology

196Citations
N/AReaders
Get full text

Hemodynamics and viability of acute neurovascular island skin flaps in rats

182Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Natural Hirudin Increases Rat Flap Viability by Anti-Inflammation via PARs/p38/NF- B Pathway

28Citations
N/AReaders
Get full text

Low-level laser therapy and light-emitting diode effects in the secretion of neuropeptides SP and CGRP in rat skin

24Citations
N/AReaders
Get full text

The effect of microneedling with a roller device on the viability of random skin flaps in rats

23Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

De Godoy, G. R., Liebano, R. E., Corrêa, J. B., Hochman, B., & Ferreira, L. M. (2010). Capsaicin on the viability of random-pattern skin flaps in rats. Acta Cirurgica Brasileira, 25(5), 440–443. https://doi.org/10.1590/S0102-86502010000500010

Readers' Seniority

Tooltip

Professor / Associate Prof. 1

50%

PhD / Post grad / Masters / Doc 1

50%

Readers' Discipline

Tooltip

Medicine and Dentistry 3

60%

Biochemistry, Genetics and Molecular Bi... 1

20%

Nursing and Health Professions 1

20%

Article Metrics

Tooltip
Social Media
Shares, Likes & Comments: 20

Save time finding and organizing research with Mendeley

Sign up for free