Predicting cancer drivers: are we there yet?

Abstract

Genomic variants with a key role in causing cancer or affecting the response to cancertherapeutics need to be identified so that they can be targeted for therapy. The transFIC tool aimsto identify somatic point mutations that drive cancer in sequencing projects. This package isavailable as a web service, a stand-alone program and a website. It improves the functionalprediction scores generated by popular established prediction tools and will be useful to cancerresearchers.See research article: http://genomemedicine.com/content/4/11/89. © 2012 BioMed Central Ltd.