The method to encourage biological cell division with vibration and circulation technique using optical manipulating

Abstract

A dual-beam trapping method was proposed and discussed for the three-dimensional optical trapping of a micro- particle. Cycling the two laser beams from optical fiber ends which were shifted a few (∼10 μ m) in horizontaldirection, the micro-particle set into an oscillatory circular motion. This method can pick up and circulate a microparticle against gravity. This micro-particle manipulation and analytical technology can be integrated on a Lab-on-a-Chip device. Generally it is known that mechanical stimulus influences cell growth speed. © Springer-Verlag 2010.