SP641NO HEART BEATING DONATION A VALID SOURCE OFORGANS. 2 KIDNEY TRANSPLANT`S CENTERS EXPERIENCE

Abstract

Introduction and Aims: Despite the introduction of new sources of organs, such as expanded criteria donors and living donors, still exists a large disparity between the number of patients on the waiting list and the pool of donors. We combine the two transplant centers experience in using this kind of donation as a valid source of organs. Method(s): In our study, we incluided 83 patients, between 03/01/2010 and 31/12/2014, who received a kidney transplant from non heart-beating donors (NHBD). 70% of recipients were males and mean age was 42.4 +/- 13 years. Mean dialysis time was 35.7+/- 23 months.90% of the donors were males, mean age was 42.4 +/- 13 years and mean cold ischaemia time of 11.4 +/- 4 hours. All patients recieved T-cell depleting antibody induction (rabbit antithymocyte globulin), mycophenolate and prednisone. Delayed introduction of ICN. Result(s): the median follow-up time was 28.4 +/- 16 months. We had 8,5% of primary non-function, 71% of delayed graft function. There was 2,4% of acute rejection at 1 year. Creatinine at 1degree, 3degree months, at 1degree year and the last follow-up, were: 3, 1.9, 1.7, y 1.85 mg/dl. Proteinuria at the same time: 656, 533, 483, y 429 mg/24 hours. Incidence of CMV infection was 40.3% and BK infection: 3 patients, without nephropaty. 2 patients died at inmediate post- operative because of intestinal ischaemia and sepsis, and one more at 3 year after pulmonary embolism. Patients and graft survivals were 98 and 91%; respectively, at 1 year and 98% and 86%, respectively, at 2 year of transplant. Conclusion(s): we can conclude that despite of high rate of DGF between NHBD recipients, the long -term outcomes in survival and allograf function are similar if we compare with results from heart beating donors.