GCMS analysis, antioxidant and antibacterial activities of ethanol extract of Anisomeles malabarica (L.) R.Br. ex. Sims leaves

  • Krishna S
  • Chandrasekaran S
  • Dhanasekar D
  • et al.
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Abstract

The leaves of belonging to the family Lamiaceae was evaluated for antioxidant and Anisomeles malabaricaantimicrobial activities. The ethanol extract of leaves of revealed the Materials and methods:Anisomeles malabaricapresence of alkaloids, phenols, steroids, glycosides, etc. The total phenolic content and total flavonoid content were carried out by Folin-ciocalteau reagent and AlCl reagent methods. The antioxidant activities of ethanol extract of 3 Anisomeles malabarica were carried out by DPPH radical, Superoxide radical (O ) and ABTS radical cation · -+ 2scavenging assays, Phosphomolybdenum reduction and Fe reduction assays. The IC of DPPH ̇ radical, 3+ Results:50Superoxide radical (O ) and ABTS radical cation scavenging assays were 94.18, 65.31 and 40.84 μg/mL 2-+concentration respectively. Also, the RC of phosphomolybdenum reduction and Fe reduction were 19.16 and 34.98 503+μg/mL concentration respectively. The antibacterial activity for ethanol extract of leaves of Anisomeles malabaricawas carried out against bacterial pathogens such as , , . The Staphylococcus aureus Bacillus subtilis Proteus vulgaris major findings of GCMS analysis were Phenol, 2, 4-bis (1, 1-dimethylethyl)-, Oleic acid, Coumarine, 3-[2-(1-methyl-2-imidazolylthio)-1-oxoethyl]- exhibiting significant therapeutic applications. The results provide Conclusion:justification for the uses of ethanol extract of to treat various infectious diseases. Further the Anisomeles malabaricaethanol extract could be turned as an effective drug for cancerous cells.

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APA

Krishna, S., Chandrasekaran, S., Dhanasekar, D., & Perumal, A. (2018). GCMS analysis, antioxidant and antibacterial activities of ethanol extract of Anisomeles malabarica (L.) R.Br. ex. Sims leaves. Asian Journal of Pharmacy and Pharmacology, 5(1), 180–187. https://doi.org/10.31024/ajpp.2019.5.1.26

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