Pd-tetraethyl tetra-t-butylcalixarene-tetra(oxyacetate) complex catalyzed acylodeboronation of arylboronic acids with benzoyl chloride or acetic anhydride

Abstract

The palladium-tetraethyl tetra-t-butylcalixarene-tetra(oxyacetate) complex, in the form of [NaL]+[PdCl3]-, exhibited high catalytic efficiency for the acylodeboronation reaction of arylboronic acids with benzoyl chloride or acetic anhydride, producing the corresponding ketones in good to excellent yields under mild reaction conditions. Various arylboronic acids, benzoyl chlorides and acetic anhydrides were tolerated in this method. Moreover, a typical method for synthesis of acetyl aryl ketones was obtained. © 2013 ARKAT-USA, Inc.