Drug resistance pattern, related socio- demographic factors and preventive practices among MDR-TB patients: An experience from a tertiary care setting

Abstract

The emergence of resistance to anti-tubercular drugs in general is a significant public health problem that threatens Tuberculosis care and control worldwide. An observational, cross-sectional, hospital based study was conducted among MDR-TB patients to know the drug resistance pattern and the preventive practices adopted by them. A pre-designed, semi-structured questionnaire was used for collection of data. 53.7% patients were found to be resistant to Rifampicin only, 46.3% to both Rifampicin and Isoniazid. All the patients were nonreactive to ICTC testing. 53.6% of patients disposed off their sputum/ expectorations at a pot kept at bedside and later disposed at bathrooms. 29.2 % spitted at roadsides and rest in their toilets. Health education regarding spread of disease, early detection of MDR-TB by strengthened laboratory support, effective therapy, implicating innovative control measures, and applying them specially among immigrants, would interrupt the ongoing transmission and control this emerging epidemic.