Early models of rabbit cardiac fibre structure where from fitting histological fibre orientation onto finite element models. More recently models have been produced using DT-MRI. In a quantitative comparison of these models, in a selected equatorial slice the fibre helix angle has a transmural change of -111.8±30.8° (mean linear fit ± S.D.) in the histological data [H-1]), -92.4±54.5° in DT-MRI dataset [DTI-1] and -86.3±30.7° in DT-MRI dataset [DTI-2]. Variation is large due to outlier data near the RV posterior insertion, and is less when selected anatomical transmural locations are quantified; the lateral LV has a monotonic transmural change of H-1:-87.5±3.7° (mean linear fit ± S.E of slope); DTI-1: -84.8±2.2°; DTI-2:-77.7±2.5°. There is greater variation in the transmural change of the transverse angle than the helix angle (DTI-1, 4.6±83.0° (mean linear fit ± S.D.), pooled data). Limitations in the datasets from both methodologies are discussed in the light of this analysis. © 2009 Springer Berlin Heidelberg.
CITATION STYLE
Gilbert, S. H., Bernus, O., Holden, A. V., & Benson, A. P. (2009). A quantitative comparison of the myocardial fibre orientation in the rabbit as determined by histology and by diffusion tensor-mri. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 5528, pp. 49–57). https://doi.org/10.1007/978-3-642-01932-6_6
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