Phytosterols in low- and nonfat beverages as part of a controlled diet fail to lower plasma lipid levels

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Abstract

Dietary phytosterols have been shown to reduce plamna cholesterol concentrations when consumed in different food matrices, but their effectiveness in nonfat or low-fat beverages has not been established. The objective of this study was to examine whether phytosterols alter plasma lipid levels when incorporated into nonfat or low-fat beverages. Fifteen moderately hypercholesterolemic men and women consumed three precisely controlled diets for periods of 21 days each in random order. Diets contained either a nonfat placebo beverage (NF), a beverage that is nonfat with added phytosterols (NFPS), or a beverage that is low in fat with added phytosterols (LFPS). Total cholesterol concentrations were not different between groups at endpoint, decreasing (P < 0.05) equally by 8.5%, 11.6%, and 10.1% with NF, NFPS, and LFPS consumption, respectively. There was no effect of dietary treatment on LDL cholesterol concentrations, which decreased over time (P < 0.05) by 5%, 10.4%, and 8.5% with NF, NFPS, and LFPS, respectively. HDL cholesterol and triacylglycerol concentration were unaffected by the diets. Provision of phytosterols as part of nonfat and low-fat beverages did not exert any greater hypocholesterolemic effect than a nonfat placebo beverage. These results show that intake of phytosterols in a low-fat beverage format is not efficacious for lipid level modification.-Jones, P.J. H., C. A. Vanstone, M. Raeini-Sarjaz, and M-P. St-Onge. Phytosterols in low- and nonfat beverages as part of a controlled diet fail to lower plasma lipid levels.

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Jones, P. J. H., Vanstone, C. A., Raeini-Sarjaz, M., & St-Onge, M. P. (2003). Phytosterols in low- and nonfat beverages as part of a controlled diet fail to lower plasma lipid levels. Journal of Lipid Research, 44(9), 1713–1719. https://doi.org/10.1194/jlr.M300089-JLR200

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