A receptor that lets dementia-associated tau proteins into neurons

  • Deinhardt K
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Abstract

In many neurodegenerative disorders, the spread of protein aggregates underlies disease progression in the brain. A receptor molecule has now been found that mediates the neuronal uptake of one such harmful protein. LRP1 protein mediates propagation of tau in the brain.

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Deinhardt, K. (2020). A receptor that lets dementia-associated tau proteins into neurons. Nature, 580(7803), 326–327. https://doi.org/10.1038/d41586-020-00874-z

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