Experimental trachoma produced by cultured virus

Abstract

A case is described of the experimental inoculation of a human volunteer with a virus isolated from a trachomatous patient and subjected to serial passage in the laboratory. The typical clinical and histological picture of trachoma resulted, with the development of inclusion bodies, and the virus was again recovered from the CQnjunctiva. The evidence that this virus is the causative agent in trachoma is therefore strong. In view of their possible interest in further investigations, two other inoculation experiments of a less conclusive nature are also described.