Ensembl 2024

Abstract

Ensembl ( https://www.ensembl.org ) isã freelyã vãilable genomic resource that has produced high-qualityãnnotations, tools,ãnd services for vertebratesãnd model organisms for more than two decades. In recent years, there has beenã dramatic shift in the genomic landscape, withã large increase in the numberãnd phylogenetic breadth of high-quality reference genomes,ãlongside majorãdvances in the pan-genome representations of higher species. In order to support these effortsãndãccelerate downstream research, Ensembl continues to focus on scaling for the rapidãnnotation of new genomeãssemblies, developing new methods for comparativeãnalysis,ãnd expanding the depthãnd quality of our genomeãnnotations. This year we have continued our expansion to support global biodiversity research, doubling the number ofãnnotated genomes we support on our Rapid Release site to over 1700, driven by our close collaboration with biodiversity projects suchãs Darwin Tree of Lif e. W e ha v eãlso strengthened support f or k e yãgricultural species, including the first regulatory builds for farmedãnimals,ãnd have updated k e y toolsãnd resources that support the global scientific communit y, notãbly the Ensembl Variant Effect Predictor. Ensembl datã, soft ware,ãnd toolsãre freelyã vãilable.