Lipase inhibitory activity in alcohol extracts of worldwide occurring plants and propolis

Abstract

In the search for lipase inhibitory agents, 144 alcohol plant extracts and propolis were screened for pancreatic lipase activity in vitro using methods with methylresorufin and triolein as substrates. Ethanol extracts of Linum usitatissimum (oil flax) and Helianthus annuus (sunflower seeds) showed the strongest lipase inhibitory actions with ID50 values of 1:370 and 1:166, respectively. Copyright © 2008 John Wiley & Sons, Ltd.