Personalized Skin Care Service Based on Genomics

Abstract

The condition of people’s skin is not only affected by environmental and psychological factors such as diet, sports, sleep and mood, genetic factors also play a very important role. Numerous genes have been identified to have associations with people’s skin color, skin inflammation, skin type, sensitivity, and so on; and many genes are connected to the regulation of the synthesis of functional proteins which are related to the skin condition such as inflammation sensitivity, anti-oxidation, anti-glycosylation, aging, collagen regeneration, moisturizing and etc. In addition, loci polymorphisms are important contributors to the occurrence, development and prognosis of various skin diseases. In terms of skin nutrition, vitamins play an important role in maintaining skin balance, and the deficiency of vitamins may cause dull complexion, lack of luster and the other skin problems. In this paper, we first describe the genes (such as MC1R, ASIP and BNC2) that are related to skin conditions including sun sensitivity, skin moisturizing function, oxidative stress, stretch marks, and skin inflammation. Then we describe the relationships between nutrients (such as vitamin A and vitamin C) and healthy skin. Finally, we design and implement a personalized skin care service consists of genetic testing, personalized nutrition for healthy skin, and personalized skin care cosmetics recommendation.