Backstepping Nonlinear Control for Blood Glucose Based on Sliding Mode Meal Observer

Abstract

Diabetes is one of the most critical diseases in the world which requires measuring the concentration of glucose also the injection of insulin to control the glucose rate in the body. The proposed controller is applied to the Bergman’s three-state minimal patient model, where the model is considered certain but with unknown meal. In the present work, a nonlinear controller is designed to control the concentration of glucose based on the Backstepping approached with a sliding mode for observing the disturbance meal. So will have estimated the meal and have canceled the effect that the glucose concentration has regulating to the basal level. The effectiveness of the proposed controller, which represent the insulin dose, is proved via simulating the Bergman’s model with designed controller via MATLAB Simulink software.  The result clarify the ability and the robustness of the proposed controller.