Modeling and analysis of gene regulatory networks

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Abstract

This chapter describes basic principles for modeling genetic regulatory networks, using three different classes of formalisms: discrete, hybrid, and continuous differential systems. A short review of the mathematical tools for each formalism is presented. Based on several simple examples, which are worked out in detail, this chapter illustrates the study and analysis of the networks' dynamics, their temporal evolution and asymptotic behaviors.

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Bernot, G., Comet, J. P., Richard, A., Chaves, M., Gouzé, J. L., & Dayan, F. (2014). Modeling and analysis of gene regulatory networks. In Modeling in Computational Biology and Biomedicine: A Multidisciplinary Endeavor (Vol. 9783642312083, pp. 47–80). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-31208-3_2

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