Recent insight has been made regarding the biological role(s) for selenoprotein K (SelK) in humans and other organisms. Suggested functions for mammalian SelK include protection against oxidative stress in cardiomyocytes, regulation of endoplasmic reticulum (ER) stress in HepG2 cells, and facilitation of calcium flux in immune cells during receptor-mediated activation. The data supporting these functions as well as other aspects of SelK are summarized in this chapter.
CITATION STYLE
Hoffmann, P. R. (2012). An emerging picture of the biological roles of selenoprotein K. In Selenium: Its Molecular Biology and Role in Human Health (Vol. 9781461410256, pp. 335–344). Springer New York. https://doi.org/10.1007/978-1-4614-1025-6_26
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