Studies were made of polyamine and Mg++ effects on rat liver mitochondrial alpha ketoglutarate oxidase (alphaKGO) and succinoxidase (SO). High spermidine levels suppress S3 and S4 of alphaKGO at 0.6-1.17 mM Mg++: some combinations of it and Mg++ increase the respiratory control ratio (RCR). Spermine suppresses S4 of alphaKGO and increases the RCR but suppresses the RCR of SO at high levels. In heat-acclimated (HA) animals in which we have studied only spermine effects on alphaKGO, RCRs of HA rats are greatly increased compared to those of controls.
CITATION STYLE
Chaffee, R. R., Arine, R. M., Rochelle, R. H., & Walker, C. D. (1978). Polyamine and magnesium effects on mitochondrial respiration in control and heat-acclimated rats. Experientia. Supplementum, 32, 95–99. https://doi.org/10.1007/978-3-0348-5559-4_10
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