This chapter summarizes the main achievements in quantum chemical modeling of metal-nucleic acid interactions. The topics discussed cover a wide range of problems taken from bio-inorganic chemistry starting from the nature of metal-nucleobase and metal-phosphate interactions, through joint binding modes to the phosphate and nucleobase moieties in nucleosides, up to the mechanism of action of platinum-based metallodrugs. The examples shown are of biological relevance and are aimed at understanding experimentally known phenomena. © 2006 Springer.
CITATION STYLE
Šponer, J. E., Burda, J. V., Leszczynki, J., & Šponer, J. (2006). Interaction of metal cations with nucleic acids and their building units: A comprehensive view from quantum chemical calculations. In Computational Studies of RNA and DNA (pp. 389–410). Springer Netherlands. https://doi.org/10.1007/978-1-4020-4851-3_15
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