MSMS: A coalescent simulation program including recombination, demographic structure and selection at a single locus

261Citations
Citations of this article
324Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Motivation: We have implemented a coalescent simulation program for a structured population with selection at a single diploid locus. The program includes the functionality of the simulator ms to model population structure and demography, but adds a model for deme-and time-dependent selection using forward simulations. The program can be used, e.g. to study hard and soft selective sweeps in structured populations or the genetic footprint of local adaptation. The implementation is designed to be easily extendable and widely deployable. The interface and output format are compatible with ms. Performance is comparable even with selection included. © The Author(s) 2010. Published by Oxford University Press.

Cite

CITATION STYLE

APA

Ewing, G., & Hermisson, J. (2010). MSMS: A coalescent simulation program including recombination, demographic structure and selection at a single locus. Bioinformatics, 26(16), 2064–2065. https://doi.org/10.1093/bioinformatics/btq322

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free