Breast cancer stem cells are regulated by cell intrinsic pathways as well as by elements in the tumor microenvironment. New evidence suggests that an important interaction between the interleukin (IL)-8 receptor CXCR1/2 and HER2 is involved in this regulation. Simultaneous targeting of these pathways provides a novel therapeutic approach. © 2012 American Association for Cancer Research.
CITATION STYLE
Korkaya, H., & Wicha, M. S. (2013). Breast cancer stem cells: We’ve got them surrounded. Clinical Cancer Research, 19(3), 511–513. https://doi.org/10.1158/1078-0432.CCR-12-3450
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