Breast cancer stem cells: We've got them surrounded

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Abstract

Breast cancer stem cells are regulated by cell intrinsic pathways as well as by elements in the tumor microenvironment. New evidence suggests that an important interaction between the interleukin (IL)-8 receptor CXCR1/2 and HER2 is involved in this regulation. Simultaneous targeting of these pathways provides a novel therapeutic approach. © 2012 American Association for Cancer Research.

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Korkaya, H., & Wicha, M. S. (2013). Breast cancer stem cells: We’ve got them surrounded. Clinical Cancer Research, 19(3), 511–513. https://doi.org/10.1158/1078-0432.CCR-12-3450

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