Crystal structure of (±)-5-benzoyl-2,3-dihydro-1H-pyrrolidine-1-carboxylic acid, ketorolac

Abstract

The title compound, (±)-5-benzoyl-2,3-dihydro-1H-pyrrolidine-1-carboxylic acid, C15H13NO3, also known as Ketorolac, crystallizes in the orthorhombic space group Pbca with unit-cell parameters: a = 7.0857(2), b = 8.0605(3), c = 43.9209(13)Å, α = β = γ 90.0000°, Z = 8. The dihedral angle between the mean planes of the benzyl and pyrrolidine groups is 45.7(9)°. Intermolecular hydrogen bonding C-H···O interactions and π-π stacking interactions between nearby pyrrolidine rings influence the twist angle between these two groups as well as crystal packing effects. 2008 © The Japan Society for Analytical Chemistry.