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Lymphodepleting conditioning regimens

Springer International Publishing, (2022), 131-133
DOI: 10.1007/978-3-030-94353-0_25
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Abstract

Lymphodepleting conditioning regimens are essential for the success of CAR-T cell treatment. Their importance in the proliferation and persistence of CAR-T cells has become clearer in the recent years. The suggested mechanisms are described in Table 25.1 and include the effects on immune cells and cytokines, creating an environment for optimal functioning and increasing the peak of expansion of the infused CAR-T cells (Neelapu 2019).

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APA

Mohty, M., & Minnema, M. C. (2022). Lymphodepleting conditioning regimens. In The EBMT/EHA CAR-T Cell Handbook (pp. 131–133). Springer International Publishing. https://doi.org/10.1007/978-3-030-94353-0_25

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