We report a method for the direct Chan–Lam coupling of arylboronic acid N-methyliminodiacetic acid esters (ArBMIDA) with amine and alcohol nucleophiles. A wide range of C−N and C−O cross-coupled products are obtained in 34–99 % yield (34 examples). This method serves to expand the scope of organoboron components that can be used directly in this oxidative coupling reaction and provides opportunities for streamlining synthesis.
CITATION STYLE
Halford-McGuff, J. M., Israel, E. M., West, M. J., Vantourout, J. C., & Watson, A. J. B. (2022). Direct Chan–Lam Amination and Etherification of Aryl BMIDA Reagents. European Journal of Organic Chemistry, 2022(45). https://doi.org/10.1002/ejoc.202200993
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