Systemic therapy

Abstract

In many dermatological, allergic, and venereal diseases, topical treatment is not sufficient in certain phases/stages and systemic therapy is required. The indication must always be established correctly, contraindications observed, and the expected benefit weighed against possible adverse drug reactions (ADRs). In comparison with topical treatment, systemic treatments often have more intensive and faster effects and are easier to control. Disadvantages are the ADRs in other organ systems and interactions with other drugs, especially in elderly patients.