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The potential of bioorthogonal chemistry for correlative light and electron microscopy: a call to arms

Journal of Chemical Biology
DOI: 10.1007/s12154-015-0134-4
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Abstract

With correlative light and electron microscopy (CLEM), the ultrastructural cellular location of a biomolecule of interest can be determined using a combination of light microscopy (LM) and electron microscopy (EM). In many cases, the application of CLEM requires the use of markers that need to be attached to a biomolecule of interest to allow its identification and localization. Here, we review the potential of bioorthogonal chemistry to introduce such markers for CLEM.

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CITATION STYLE

APA

van Elsland, D. M., Bos, E., Overkleeft, H. S., Koster, A. J., & van Kasteren, S. I. (2015, October 1). The potential of bioorthogonal chemistry for correlative light and electron microscopy: a call to arms. Journal of Chemical Biology. Springer Verlag. https://doi.org/10.1007/s12154-015-0134-4

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