In this chapter, we describe a robust normalization method for single-cell RNA sequencing data. The procedure, SCnorm, is implemented in R and is part of Bioconductor. Also included in the package are diagnostic functions to visualize normalization performance. This chapter provides an overview of the methodology and provides example work-flows.
CITATION STYLE
Bacher, R. (2019). Normalization for single-cell RNA-seq data analysis. In Methods in Molecular Biology (Vol. 1935, pp. 11–23). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9057-3_2
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