The relationship between antithyroid antibody and pregnancy outcome in invitro fertilization and embryo transfer

Abstract

Background of the study: One type of assisted reproductive technique is intracytoplasmic sperm injection (ICSI) Despite use ofintracytoplasmic sperm injectionICSI it remain has low birth rate due to failure rate there are many markers associated with poor predict the outcome one of these factor effect outcome inintracytoplasmic sperm injection ICSI presence of antithyroid antibody ineuthyroid patient Aim of study: To examine the effect of antithyroid antibody on pregnancy results following the in vitro fertilization and fetus transmit Methods and patients: Cross section study conducted at AL-Sader infertility center atotal of eighty one Iraqi women were enrolled in this study of them 22positive antithyroid antibody,59 negative antithyroid antibody were undergone intra-cytoplasmic sperm injection ICSI in Al-Sader infertility center. The group of the study involved onlyeuthyroid women outwardly any clinically showed autoimmune illness. Result:there was higher significant difference p value<0.004 in fertilization rate number of available embryos p value<0.003 and number of transfer embryos p value< 0.001among study group which was higher in group of women with antithyroid negative followed by,group with antithyroid positive in infertile euthyroid women Conclusion:patients with antithyroid antibody associated with poor pregnancy outcome in infertile euthyroid women undergoingintracytoplasmic sperm injection ICSI.