New α-tetralonyl glucosides from the fruit of Juglans mandshurica

Abstract

Five new α-tetralonyl glucosides, juglanosides A-E (1-5) were isolated from the fresh rejuvenated fruit of Juglans mandshurica. Their structures were elucidated as (4S)-4-hydroxy-α-tetralone 4-O-β-D-glucopyranoside (1), (4S)-4,5-dihydroxy-α-tetralone 4-O-β-D-glucopyranoside (2), (4S)-4,6-dihydroxy-α-tetralone 4-O-β-D-glucopyranoside (3), (4S)-4,5,8-trihydroxy-α-tetralone 4-O-β-D-glucopyranoside (4), and (4S)-4,5,8-trihydroxy-α-tetralone 5-O-β-D-glucopyranoside (5) on the basis of spectroscopic analysis and chemical evidence. © 2004 Pharmaceutical Society of Japan.