The enteroendocrine system coordinates the physiological response to food intake by regulating rates of digestion, nutrient absorption, insulin secretion, satiation and satiety. Gut hormones with important anorexigenic and/or insulinotropic roles include glucagon-like peptide 1 (GLP-1), peptide YY (PYY3–36), cholecystokinin (CCK) and glucose-dependent insulinotropic peptide (GIP). High BMI or obesogenic diets do not markedly disrupt this enteroendocrine system, which represents a critical target for inducing weight loss and treating co-morbidities in individuals with obesity.
CITATION STYLE
Miedzybrodzka, E. L., Reimann, F., & Gribble, F. M. (2022). The Enteroendocrine System in Obesity. In Handbook of Experimental Pharmacology (Vol. 274, pp. 109–129). Springer Science and Business Media Deutschland GmbH. https://doi.org/10.1007/164_2022_582
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