EFFECT OF SULFATION ON THE STRUCTURE AND ANTICOAGULANT ACTIVITY OF ULVAN EXTRACTED FROM GREEN SEAWEED ULVA RETICULATA

Abstract

Ulvans are sulfated polysaccharides derived from the cell wall of green seaweeds. Thechemical structure of ulvan extracted from Ulva reticulata is reported, focusing on investigationof the sulfated modification of the ulvan and the changes in structure and anticoagulant activity.The results showed that sulfated modification was able to change the ulvan conformationalstructure and markedly enhance its anticoagulant activity.